Henry's Thread

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Lynx
RESIST

Post   » Sun Dec 07, 2008 11:01 pm


Sorry to seem kind of dense, but to be sure of how you want to change it, can you post how you want that post to read?

Talishan
You can quote me

Post   » Mon Dec 08, 2008 12:11 am


You're not dense. It's confusing (thanks to yours truly :-P)

***********************

"To recap, for JoePig and others who have asked about Actigall dosing, this is what we have so far. (Tracis, please check me and make sure I'm not missing anything when you have a chance.)


Protocol #1, from Dr. Ella Ahearn, Animal Hospital of Sandy Springs, Atlanta, Georgia:

Mix 1 300 mg capsule in 4 mL of liquid. Administer 0.25 cc's of this once a day for 4 days. After that, administer 0.15 cc's of this daily.


Protocol #2, from Vicki of Jack Pine Guinea Pig Rescue's vet:

http://www.guinealynx.info/forums/viewtopic.php?p=1237793#1237793

Mix one 300 mg capsule Actigall/Ursodiol with 2cc liquid.
Give 1/2 cc (.5 cc) once daily for 8 days

Then mix one 300 mg capsule Actigall/Ursodiol with 4cc liquid
Give 1/2 cc (.5 cc) once daily for a 1-2 months or until stone or sludge is confirmed gone by X-ray.

After that administer lower (weaker) dose once every other day indefinitely if it seems to have helped.


Protocol #3, from Dr. Miller for TWP and TWP_2's Henry:

http://www.guinealynx.info/forums/viewtopic.php?p=1462369#1462369

Henry started out on 0.5 mL of a 150 mg/mL compound for eight days. After that, he has been on a maintenance dose of 0.5 mL of a 75 mg/ML compound once a day.


I am assuming all protocols are using a 300 mg ursodiol capsule. This contains a powder that readily mixes with water."

***********************

I am really sorry to be such a PITA. I just don't want any casual reader to overdose their pig.

Tracis
Let Sleeping Pigs Lie

Post   » Mon Dec 08, 2008 12:57 am


This is wonderful, Talishan!

Protocol #2 was also used successfully by Dr. Ridgeway for Valentine:

http://www.guinealynx.info/forums/viewtopic.php?p=1427912#1427912

"The dosage we used was:
Mix one 300 mg capsule of Ursodiol (Actigall®) with 2 mls of mixing liquid, give 0.5 cc orally one time a day for 8 days, then mix one 300 mg capsule of Ursodiol (Actigall®) with 4 mls of mixing liquid, give 0.5 cc orally daily for 1 – 2 months.

Sincerely,
William V. Ridgeway, Jr., D.V.M.
Long Beach Animal Hospital, Inc.
3816 E. Anaheim Street
Long Beach, CA 90804-4005"

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sef1268

Post   » Mon Dec 08, 2008 6:36 am


This is good information. Is there any way to create a cross-link back to this thread from the Stones page?

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Lynx
RESIST

Post   » Mon Dec 08, 2008 9:52 am


I edited her earlier post with a link back to the new post.

Tracis, do you have an actigall thread in the Records forum? What you could do is copy Talishan's info (or you could do it, Talishan) and add Tracis info with pertinent links added.

It is a real bonus for links to have some of the advice quickly available to read. I could also link from the stones page to an actigall records thread.

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sef1268

Post   » Mon Dec 08, 2008 10:10 am


Super. I'm faxing this info over to my vet this morning as an "FYI." Thinking it would be good for her to have a jumpstart on it now, vs. waiting until one of our guys actually has another stone.

Tracis
Let Sleeping Pigs Lie

Post   » Mon Dec 08, 2008 10:43 am


In the Records Forum now:

LINKS - Actigall® / Ursodiol

I'm still adding other links at the end of the page.

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Lynx
RESIST

Post   » Mon Dec 08, 2008 12:04 pm


Looks great! I'll go add a link to Actigall thread in the guide. Maybe you can also add the Dr. Ridgeway quote you found to your links thread? (it looks most helpful)

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Lynx
RESIST

Post   » Mon Dec 08, 2008 3:09 pm


p.s. I also updated the stones page with a link to your link and changed another Tracis link from the forum one to your new Records one.

Tracis
Let Sleeping Pigs Lie

Post   » Mon Dec 08, 2008 3:12 pm


Thank you, Lynx. I added Dr. Ridgeway's quote, too.

Talishan
You can quote me

Post   » Mon Dec 08, 2008 9:08 pm


The work you both have done looks just great. Thank you for making coordinated sense out of my mess. :-p

TwoWhitePiggies

Post   » Mon Dec 08, 2008 11:15 pm


Ditto, Talishan.

TwoWhitePiggies

Post   » Tue Jan 06, 2009 10:46 pm


Henry seems to be doing great. He's eating, drinking, playing with Frost, and keeping a good, steady weight. He is periodically putting out a puddle of sludge, but it isn't too worrisome.

The strange thing is that he's taken to sleeping in weird places. He never before was the kind of pig to sleep smack on top of the hay pile, and now that's what I've seen him doing. He also will sleep in random places in the cage, with his facing the coroplast with his nose touching the coroplast. It's very odd.

Also, if either of us pets Frost, he'll run over and stick his head under our hands to get the attention. Which is amusing. And he doesn't accept you petting him with one hand and Frost the other. He wants all the love.

Can guinea pigs grow a teensy bit senile in their sunset years?

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becksters
Two Time Supporter

Post   » Tue Jan 06, 2009 11:10 pm


That sounds kind of sweet though! The old guy just wants some loving!

Matilda sits facing the corners of the coroplast, and butts her nose against the corners as well. I attribute that to her cataract and lack of what little vision she had to begin with and possibly old age as well but who knows.

Glad he's doing well though - question, will you re x-ray in a few months to check again? Or just wait and see and hope the agitall is doing it's job?

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HenriettaG

Post   » Tue Jan 06, 2009 11:57 pm


Our Lionel is "wierd" too. He's not a very consistent pig. Sometimes he likes the fleece bed, sometimes he likes to flake out on a blanket. I think they just change like we do.

TwoWhitePiggies

Post   » Wed Jan 07, 2009 12:30 am


becksters - We've gone back and forth on whether or not to x-ray him again. I think at this point, as long as he's acting healthy, keeping his weight up, and not showing signs of pain, we won't traumatize him with a trip to the vet.

We've all batted around this theory that the Cavy Cuisine might somehow be connected to stone formation. What I'm wondering is if that is only true for pigs who were switched to Oxbow after adulthood. My two youngest pigs were raised on it from birth and then were switched to KM's pellets. Frost and Linus are both just a little over two years old and don't seem to have any problems. All of the other pigs - five of them - started Oxbow when they were mature, and they all developed stones after the switch.

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sef1268

Post   » Wed Jan 07, 2009 7:10 am


That's a good question. We adopted Otis when he was about a month old, and he was on, I think, Kaytee, for a few months, and then we switched over to Oxbow and he was on that up until around Jan./Feb/Mar. of 2008 (when Zachary was battling all of his stone problems). He turned 5 in October; has been on Kleenmama since early 2008, but yeah -- I have to wonder if Cavy Cuisine somehow has a "cumulative" effect on the bladder. I don't see how, but who knows.

Did you ever have your water evaluated, TWP?

I"m going to be pursuing that again (another GL member kindly offered to help; I need to follow up with her this week).

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sef1268

Post   » Wed Jan 07, 2009 7:22 am


Also wanted to add...I contacted Dr. Hawkins of UC Davis awhile back (before Otis was diagnosed with a stone), asking if she had an opinion on the number of cases we're seeing of guinea pigs with stones that have also been on Oxbow pellets. I cited my own experiences as well as some of the experiences of other GL members. She wrote back and essentially said that the role of diet is unclear, but she felt that the brand of pellets was less of a concern than the amount of pellets in the diet. That is, pigs with a diet consisting largely of pellets were at a higher risk.

That may be true, but I've always been careful about the amount of pellets I feed. It's certainly the smallest part of their diet; each pig gets roughly 1/8 cup a day, divided into two feedings, with considerably more than a cup of fresh veggies at each feeding, and unlimited hay. Other than one male who was over-weight (3+ lbs.) when we got him and has continued to be on the hefty side, our boys' average weight is around 2 lbs. 6 oz.


I just don't buy that something in Oxbow pellets aren't a contributing factor in some way.

TwoWhitePiggies

Post   » Wed Jan 07, 2009 9:49 am


I just a measuring cup to measure out pellets, so I don't believe we're overfeeding the pellets. I'm glad you followed up with UC Davis, though, sef.

And as far as we can tell based on Jim's conversation with the water department, our water isn't a problem.

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becksters
Two Time Supporter

Post   » Wed Jan 07, 2009 10:38 am


I wonder if the high incidents of stones is becoming something like the high incident of ovarian cysts in sows. Is it possible it's just becoming one of their many prone illnesses?

I suppose the unfortunate amount of careless breeding doesn't help either with the gene pool and maybe because of that these things are becoming more pronouced now and as time goes on? Just another thought.

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