Henry's Thread
We also wonder if there is some sort of low-grade viral or bacterial infection that might make a pig more likely to develop stones - and thus something that could be spread from pig to pig?
The last time our bladder stone pig had surgery, we had a a culture done. I do not know why we never had one done before as the little guy had a staph infection. It was treatable, but not by the oral antibiotics we were using!
Considering how messed up this pig was when we first got him and how early on he got bladder stones, I wonder if he hadn't had this staph infection the whole time.
Considering how messed up this pig was when we first got him and how early on he got bladder stones, I wonder if he hadn't had this staph infection the whole time.
Question/Request for clarification in the Records Forum:
In Protocol #1 and Protocol #3 could a small piece of information be added for people like myself? (Alright, idiots, dummies, knuckleheads, etc.) If this is possible, Thanks!
In Protocol #1 it reads:
In Protocol #3 it reads:
In Protocol #1 and Protocol #3 could a small piece of information be added for people like myself? (Alright, idiots, dummies, knuckleheads, etc.) If this is possible, Thanks!
In Protocol #1 it reads:
Could it be added "Mix 1 300 mg capsule {WHAT} in 4 mL of liquid {WHAT}.Mix 1 300 mg capsule in 4 mL of liquid. Administer 0.25 cc's of this once a day for 4 days. After that, administer 0.15 cc's of this daily.
In Protocol #3 it reads:
Could that also be updated to say "Henry started out on 0.5 mL of a 150 mg/mL compound {OF WHAT?} for eight days. After that, he has been on a maintenance dose of 0.5 mL of a 75 mg/mL compound {OF WHAT} once a day. (Note: 1 mg/mL = x cc's)Henry started out on 0.5 mL of a 150 mg/mL compound for eight days. After that, he has been on a maintenance dose of 0.5 mL of a 75 mg/mL compound once a day.
I keep coming back to the idea my vet found that was pretty glossed over as crazy here, oxalobacter. It's a tiny aneorobic bacteria that's supposed to metabolize oxalic acid. It's highly sensitive to fluoroquinolone antibiotics (Baytril, cipro, etc). Since gut bacteria are populated from the mother, if mom were treated with a fluoroquinolone, especially in some stupid way like constant low doses in the drinking water, the pups could then be at high risk of stones because they're born never metabolizing oxalic acid properly without the bacteria since they couldn't acquire it from mom. Not only would this explain "heritable" differences, it would explain regional frequencies too since pigs in a given area are likely to a) be related and b) come from the same crappy mill. Maybe it's stupid and crazy, but it doesn't seem illogical.
If you go to Pubmed (http://www.ncbi.nlm.nih.gov/sites/entrez) and search "oxalobacter" you can read abstracts that describe the concept. The same articles I found are still online. They have a little green line "Free article in PMC."
- Bytxlaura
- Remembering Nemo
Sef, if you take the amount of pellets fed into consideration, I - from my experiences - would rule it out. I have fed 1/8 cup of Oxbow every two days per pair of pig (2 of them) for 3 years and have switched to KM when one pig developed stones and 3, potentially 4, developed sludge. They currently get one tablespoon of KM per pair every two days. Veggies twice a day and unlimited hay (different kinds - bluegrass, timothy, sweet meadow). I'm keeping my fingers crossed the diet change helps :)
Perhaps it's only the fluoroquinolone antibiotics and something about guinea pig biochemistry?
Our first two pigs were treated for respiratory thing before they were a year old, but our vet, who wasn't as knowledgeable back then, treated them with...oh, my brain is blanking out. An antibiotic that's actually better suited to gut problems. Anyway, Sully developed his first stone about eight months later, and then Gilbert developed his about six months after that.
Henry was treated with TMS and Baytril at one point, and developed stones about two years later.
Widget was never treated with antibiotics by me before developing a stone, but I can't say if the rescue may have treated him.
Tom started showing signs of a URI the day we brought him home, so he was treated with TMS.
Our first two pigs were treated for respiratory thing before they were a year old, but our vet, who wasn't as knowledgeable back then, treated them with...oh, my brain is blanking out. An antibiotic that's actually better suited to gut problems. Anyway, Sully developed his first stone about eight months later, and then Gilbert developed his about six months after that.
Henry was treated with TMS and Baytril at one point, and developed stones about two years later.
Widget was never treated with antibiotics by me before developing a stone, but I can't say if the rescue may have treated him.
Tom started showing signs of a URI the day we brought him home, so he was treated with TMS.
- Sef
- I dissent.
Of our stone pigs (Sidney, Zachary, Sebastian and now Otis), only Sidney and Zachary were on Bactrim for various things. Sidney came to us a URI; quickly cleared up after a single round of Bactrim. Zachary was on Bactrim and-on-off for about a year and a half for what we thought was I/C.
Bassy was never on AB's (and we got him very young), and neither was Otis.
It's interesting, though, and I do want to read the article when I get a chance. I wonder if there is a connection between the fact that Zachary had numerous, very aggressive stones (forming at an alarming rate) and was on Bactrim for an extended period of time.
Bassy was never on AB's (and we got him very young), and neither was Otis.
It's interesting, though, and I do want to read the article when I get a chance. I wonder if there is a connection between the fact that Zachary had numerous, very aggressive stones (forming at an alarming rate) and was on Bactrim for an extended period of time.
Sef, Bactrim wouldn't be an issue. It's only Baytril and similar meds which actually means it isn't as big of a risk to humans since this class of antibiotics still isn't prescribed all that often and is never given to children. What I imagine is early exposure or a life-long absence of the bacteria (i.e. mom was treated heavily prior to pregnancy) would be more likely to cause stones, especially if combined with poor diet. LOTS of pigs are treated with Baytril. Considerably fewer develop stones so there has to be another factor that goes in there too.
So if Bassy and Otis's mom was treated they could have been born with no ability to acquire this bacteria at all. It occurs naturally in the feces of birds apparently so "wild" cavies get it through eating seeds and dirt on occasion. Domestic cavies only have hereditary exposure through mom to populate good gut bacteria.
So if Bassy and Otis's mom was treated they could have been born with no ability to acquire this bacteria at all. It occurs naturally in the feces of birds apparently so "wild" cavies get it through eating seeds and dirt on occasion. Domestic cavies only have hereditary exposure through mom to populate good gut bacteria.