Guinea Pig with Nephrotic Syndrome, Advice on Treatment?

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Lynx
RESIST

Post   » Thu Oct 22, 2015 9:59 pm


I have added your necropsy report with a link back to this thread in the Records forum, where it will be easier to find.
http://www.guinealynx.info/records/viewtopic.php?t=238

I am so sorry you lost her.

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ph08fhf

Post   » Mon Oct 26, 2015 10:43 pm


I'm very glad the information is available on here for others.

It just occurred to me that I should mention that Barbara was an LMRR pig. She was one of the pigs I 'posted about back in 2012 when I was worried that K might try to take them back.

Not sure why I felt the need to share that with you. She saw so much in her short life. She really was an amazing pig. She could eat 27 blueberries in one sitting.

Barbara-Ann, 2011-2015. <3 <3

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I miss her.

GrannyJu1
Armcavy

Post   » Tue Oct 27, 2015 5:35 pm


((ph08fhf)) Sending hugs.

Talishan
You can quote me

Post   » Thu Oct 29, 2015 3:26 pm


What a wonderful tribute to her your pictures are.

She is a gorgeous pig. We will all remember her and honor her being.

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ph08fhf

Post   » Sat Oct 31, 2015 1:18 pm


Some extra details about the necropsy from speaking with my vet:

It is very difficult to determine the actual cause of death. There was bleeding around the heart which may have been caused by the blood draw (which was happening when she stopped breathing) or may have been caused by attempts to resuscitate (she was given several injections (epinephrine?) and CPR given for some time.

Barbara also had a number of other medical issues going on that were not diagnosed. The most notable of which is the heart disease. It is unclear whether this in connected, but it is probable that it contributed to hear death in some way.

The Total Protein Creatine number was shocking. My vet explained that in dogs they would expect to see a number as high as 5 - anything over 1 is considered abnormal. Barbara's number was 30. If I remember rightly, my vet said that this indicate Barbara's condition was much worse than expected, and her kidneys were likely just failing to filtre any thing correctly, see also below:

They also found that the levels of waste/harmful compounds found in the blood were higher. Which indicates her kidneys were unable to filtre out these materials (i'm afraid I don't remember the names of the particular compounds)

I asked whether there was any indication that the treatment was helping. She said it was hard to say, but that, had Barbara survived that day, given her chem panel we would probably have discussed lowering the dose on enarlapril.

I asked also whether she thought there was any indication of the cause. She said this was also hard to tell, given that there was absolutely no sign of an infection (which would be most likely to cause the nephrotic syndrome) she suspected that it was a genetic condition.

I asked whether Barbara had suffered and she reassured me that given how quickly she went and her attitude that day and the type of illness, that she was sure that Barbara did not suffer and probably didn't even realise what was happening or that she was so ill.

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Lynx
RESIST

Post   » Sat Oct 31, 2015 5:39 pm


It is helpful to us for you to have added the explanation and additional info. Most of us can't really analyze a necropsy report.

I am still so sorry you lost her.

Crazy4me

Post   » Sat Oct 31, 2015 7:59 pm


I am so sorry you lost her too.

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jacqueline

Post   » Tue Nov 03, 2015 7:10 am


You clearly loved her and provide her with a soft place to live her life. She was very lucky. I'm sorry for your heartbreak. (((hugs)))

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ph08fhf

Post   » Sat Jun 11, 2016 12:56 pm


Barbara's Legacy...

When I saw my vet yesterday she told me that Barbara was going to be discussed at an upcoming veterinary conference this summer. They will discuss her diagnosis and treatment. She said that Barbara will demonstrate 'how much more we still need to learn about guinea pigs'.

She was such a special pig. It makes me so happy that she has this legacy.

<3 Barbara <3

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Lynx
RESIST

Post   » Sat Jun 11, 2016 2:00 pm


It is definitely through pet owners like you that go the extra mile and work with a good vet to find out what is going on medically that advance our understanding of illness.

I don't know if your vet intends to publish anything but whether or not, she would be more than welcome to write up a case study to be added to the appropriate area in the Records forum where it is more easily accessed.

gl/records

Talishan
You can quote me

Post   » Sun Jun 12, 2016 7:58 am


Ditto Lynx.

Barbara's greatest legacy will be to help others of her kind. And please do remember that if you had not gotten the quality of care for her that you did, Cornell (and everyone else) would not be able to learn.

That counts for a lot.

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