Sal - lump under bottom left nipple

Evangeline

Post   » Tue Mar 11, 2003 4:49 pm


Well, it sucks, but hopefully, they removed all of it before it had time to spread.

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Zoe

Post   » Wed Mar 12, 2003 12:03 am


Hey Briana. That will be wonderful if Dr. Murray managed to get it all. Poor Sal. At least he's in good hands... yours and Dr. Murray's. Keep us updated please.

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melcvt00

Post   » Thu Mar 13, 2003 10:13 am


He's already out of that 30% that aren't benign. Carcinoma is malignant. I can't remember, and I don't feel like going back through...were chest x-rays done?

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briana d

Post   » Thu Mar 13, 2003 11:01 am


I know it is malignant. I don't believe chest z-rays were done. What would be the benefits of having chest x-rays?

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melcvt00

Post   » Thu Mar 13, 2003 11:04 am


Malignant tumors metastasize. Meaning, little pieces shoot off and attach to other places. Lungs are usually the first place where new tumors grow. And guinea pigs are small enough, it's easy to do full-body x-rays. I would wait until after the incision is healed, though.

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briana d

Post   » Thu Mar 13, 2003 11:05 am


He is getting his staples out this Saturday - I'll mention this to my vet. Thanks!

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melcvt00

Post   » Thu Mar 13, 2003 11:07 am


And since that tumor was malignant, I'd recommend x-rays every 6 months.

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briana d

Post   » Thu Mar 13, 2003 11:07 am


One more question. I was told that the margins were clean. If pieces of the tumor attached somewhere else do you think the margins would still show to be clean?

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melcvt00

Post   » Thu Mar 13, 2003 11:09 am


Let me put it to you this way...all tumors like that have a blood supply. There were tiny blood vessels traveling through that tumor to keep it "alive". Before it was removed, individual cells could have been sloughed off (broken off) and gone into the blood stream. Those cells could end up anywhere.

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briana d

Post   » Thu Mar 13, 2003 11:22 am


So if cells broke off and made it to the blood stream the whole clean margin thing means nothing?

Is x-ray the only way to determine another tumor? Should I request any blood test be done or anything?

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melcvt00

Post   » Thu Mar 13, 2003 11:26 am


Clean margins mean that the tumor is unlikely to come back in that spot. You might call the vet and ask what the likelihood of that kind of tumor metastasizing is. Some don't very often.

As far as I know, x-ray or ultrasound is the most reliable way to find out if there's another one somewhere.

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briana d

Post   » Thu Mar 13, 2003 11:28 am


Thanks again!

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melcvt00

Post   » Thu Mar 13, 2003 11:32 am


No problem.

Evangeline

Post   » Fri Mar 14, 2003 3:42 pm


This is the first time I hear about those tests. Briana's vet is obviously excellent, and I wonder why he didn't suggest them. Briana, did you discuss that with him? I'm asking because it seems odd that no one here has ever been suggested them before.

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briana d

Post   » Fri Mar 14, 2003 4:25 pm


Are you referring to the x-ray or ultrasound? When I talked with Murray he was still waiting to talk with the pathologist about some additional information - I don't know what.

I've taken a lot of information from this thread and emails with pigpal and I plan to ask the vet about them tomorrow.

The only downfall with Murray is that it is almost impossible to talk to get a hold of him- he doesn't have a lot of free time.

Evangeline

Post   » Fri Mar 14, 2003 4:35 pm


Let us know what he says.

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Zoe

Post   » Fri Mar 14, 2003 5:19 pm


I'm taking my Petunia to see Dr. Murray today. He called me last week to explain to me the theory on using Polycitra for stones in pigs. I have found that he is clear about his thinking on things. He shares his thought process if you can catch him...

Good luck Briana and Sal!

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briana d

Post   » Sun Mar 16, 2003 10:55 pm


I got a copy of Sal's test results from the pathologist.

Histopath Report
Source/History
: Adult male guinea pig with rapidly growing mass associated with right teat. No evidence of reproductive system disease. Intact male. Received a 2 cm skin/covered specimen with well-demarcated mass.

Description
Representative sections of the mass are examined. The mass is present subjacent to the teat. It is fairly well demarcated but nonencapsultated and is surrounded by a peripheral margin of normal tissue ringing from .03cm and more.

The center portion of the mass consists of small tubules and cluster formed by mildly atypical cuboidal epithelial cells. Narrow bands of fibrous stroma are interspersed and the mitotic rate is approximately 1/hpf. Some of the tubules contain luminal secretory material.

There are also multifocal areas of necrosis and inflammation present within the mass. In some areas, there is also a prominent mycepithelia stroma between epithelia structures.

Microscopic findings: mammary tubular and variably cystic Adenocarcinoma, well demarcated and well differentiated, guinea pig.

Prognosis - Long term - potentially guarded.

Comments: Mammary neoplasm's can occur in both male and female guinea pigs. The majority of mammary tumors in guinea pigs are consistent with benign fibroadenomas. Approximately 30% are adenocarcinoma, as in this case.

They generally behave as local invasive tumors with rare metastasis reported. In this case, the mass was fairly well demarcated and appeared within surgical margins. This would suggest complete removal; however findings should be used in conjunction with surgical findings.

Lymphatic and/or vascular invasion were not identified; however, I cannot guarantee that they have not yet taken place.

Close monitoring of the mammary region for re-growth is suggested as well as monitoring of regional lymph nodes for any sign on enlargement that would suggest metastasis.

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briana d

Post   » Mon Mar 17, 2003 11:44 pm


Here is Sal's incision two weeks after the surgery and two days after the staples were taken out.

Image

Evangeline

Post   » Tue Mar 18, 2003 9:11 am


Wow. It healed well.

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