IVERMECTIN :: ORAL TREATMENT
IVERMECTIN ORAL DOSING GUIDELINES
Author's note: Please be sure to read the Guinea Pig Dose Guidelines. This information is not designed to take the place of veterinary care. Using a veterinarian will ensure that this product should be used and is properly administered. Incorrect use can result in fatalities.
The following chart will offer guidelines for determining an appropriate oral dose for your cavy to treat mange mites. Follow any precautions on the label, don't smoke or eat when handling product and keep it at room temperature in a dark place. Dilutions using propylene glycol can be used at a later date. Check the expiration date on the container to determine the shelf life of any product you are using. If diluting ivermectin products with water, discard after use. A dilution using vegetable oil is probably best discarded also.
All doses must be repeated in 7 to 10 days at least once. Ivermectin can be administered to pregnant cavies but is best NOT administered to the young until they are at least 340 grams in weight (12 ounces). Ivermectin can probably be safely used on lactating mothers (see discussion).
Remember that it is possible to overdose guinea pigs with ivermectin.
Weigh your pig and convert to grams if using a pound scale.
2.2 pounds = 1 kilo = 1000 grams
A twelve ounce pig = 340 grams
A one pound pig = 454 grams
A two pound pig = 909 grams
A three pound pig = 1364 grams
See Weight Conversion Chart if you need assistance.
Ivomec Injection Solution. Ivomec Injection (10 mg/ml) can be diluted with 9 parts propylene glycol or with a vegetable oil like canola.
Thoroughly mix 9 ml propylene glycol or vegetable oil with 1 ml of injectable ivermectin. Cavy owners report that propylene glycol mixes better. This mix will treat 50 kilos (110 pounds) of guinea pigs. Once diluted, the concentration is 1 mg/ml. The dose is administered orally (by mouth) using a small 1 cc needleless syringe (pictured below). These small, commonly available syringes are about 3 1/2" (9 cm) long and can usually be obtained from your vet. The dose will be a very small amount, a few drops.( Note: one ml = one cc)
1.0cc Ivomec Injection + 9.0cc propylene glycol YIELDS 1mg/ml Ivermectin Solution
Oral Dosage: 0.2mg ivermectin/kg
0.2 ml of this solution will contain 0.2 mg ivermectin.
ORAL DOSE Using Diluted Ivermectin
For a 350 gram cavy: 0.07 cc Diluted Ivermectin
For a 400 gram cavy: 0.08 cc Diluted Ivermectin
For a 500 gram cavy: 0.10 cc Diluted Ivermectin
For a 600 gram cavy: 0.12 cc Diluted Ivermectin
For a 700 gram cavy: 0.14 cc Diluted Ivermectin
For a 800 gram cavy: 0.16 cc Diluted Ivermectin
For a 900 gram cavy: 0.18 cc Diluted Ivermectin
For a 1000 gram cavy: 0.20 cc Diluted Ivermectin
For a 1100 gram cavy: 0.22 cc Diluted Ivermectin
For a 1200 gram cavy: 0.24 cc Diluted Ivermectin
For a 1300 gram cavy: 0.26 cc Diluted Ivermectin
For a 1400 gram cavy: 0.28 cc Diluted Ivermectin
For a 1500 gram cavy: 0.30 cc Diluted Ivermectin
PRINTABLE ORAL Treatment Page with Chart
Some people prefer to use a horse paste like Zimecterin or Equimectrin because of the lower cost. However, it is much more concentrated and thorough mixing is essential. Horse paste can also be diluted either with propylene glycol, vegetable oil or water (according to studies Harkness and Wagner have cited) to an approximate solution of 1mg/ml. The oral dose chart above can be used as a guide when the product is diluted according to the directions below. Cavy owners report that propylene glycol mixes best (and can be used for the second or more dose). Tepid (not hot) water also reportedly mixes well but this solution should be mixed fresh for each use and not stored. Vegetable oil tends to separate and must be mixed/shaken well before drawing each dose.
Horse Paste Solution. The horse paste sold in the U.S. comes in a tube marked for various weights of horse by pound. A whole tube contains enough ivermectin to treat a 1250 pound horse. You can use the chart above if you dilute the horse paste into a solution yielding roughly 1 mg ivermectin/ml. To do this, examine the tube and squirt a dose for a 250 pound animal into a clean jar that can be covered tightly. This dose (a portion of the whole tube) contains 22.74 mg ivermectin. Add 22.0 cc of propylene glycol, vegetable oil or water. Shake thoroughly. One cc of this mixture will contain no more than 1.00 mg ivermectin/ml. The dose is slightly less because it does not take into account the volume of the horse paste itself. Horse paste is listed in grams by weight (not a volumetric measurement) making accurate calculations difficult. As a result, the horse paste will slightly dilute the amount of ivermectin administered using this formula.
250 pound dose + 22.0cc propylene glycol YIELDS (-)1mg/ml Ivermectin Solution
The horse paste sold in other countries comes in a tube marked for various weights of horse by kilo. Evangeline uses Panomec in Canada, purchased from a vet. Panomec comes in a 6.42 g tube and treats a 600 kilo (1320 pound) horse. This 1.87% tube contains 120 mg. ivermectin. Examine the tube and squirt a dose for a 100 kilo animal into a clean jar that can be covered tightly. This dose (a portion of the whole tube) contains 20 mg ivermectin. Add 20 cc of propylene glycol, vegetable oil, or water. Shake thoroughly. One cc of this solution will also contain not more (but slightly less) than 1.00 mg ivermectin per ml.
100 kilo dose + 20.0cc propylene glycol YIELDS (-)1mg/ml Ivermectin Solution
A smaller amount can be mixed by using the markings for 25 kilos (this contains 5 mg ivermectin) and mixing thoroughly with 5 cc propylene glycol, vegetable oil or water.
25 kilo dose + 5.0cc propylene glycol YIELDS (-)1mg/ml Ivermectin Solution
Remember: Solutions using propylene glycol can be stored at room temperature in a dark place and used at a later date (check expiration date on product). If diluting ivermectin products with water, discard after use. A solution using vegetable oil is probably best discarded also.
Ivermectin products (see photos above) can generally be found at local feed stores or online.
Keep in mind, the above is intended to put ivermectin dosing into perspective. Calculations using the horse paste are not completely accurate and there may be other errors.
WARNING: Sufficient information is provided the reader to enable him/her to determine the dose independently. If you do not understand how the dose is calculated or have any questions, DO NOT ATTEMPT TO DOSE YOUR PIG. It is wise to have someone else check your calculations.
You are still advised to SEE A VET.
PRINTABLE ORAL Treatment Page with Chart